Zyvex is the first molecular nanotechnology company, with a vision of developing adaptable, affordable, molecularly precise manufacturing. This talk will show the progression from macroscopic manipulation, to meso-scale (millimeter), to micro-scale, and ultimately to nano-scale. Zyvex has several years of experience in building and selling nanomanipulation tools, as well as a number of microassembled MEMS products under development, including a miniature mass spectrometer. New work to be discussed is an approach to Atomically Precise Manufacturing, using UHV STM-mediated depassivation of silicon followed by repetitive cycles of Atomic Layer Deposition/Epitaxy to build 3D structures with atomic precision.