AVS 65th International Symposium & Exhibition
    Plasma Science and Technology Division Monday Sessions
       Session PS+PB-MoA

Paper PS+PB-MoA2
Atmospheric Pressure PE-CVD of Drug-containing Nanometric Capsules

Monday, October 22, 2018, 1:40 pm, Room 104A

Session: Plasma and Polymers: 'The Legacy of Riccardo d’Agostino and Beyond’
Presenter: Pietro Favia, University of Bari, Italy
Authors: P. Favia, University of Bari, Italy
C. Lo Porto, University of Bari, Italy
A. Treglia, University of Bari, Italy
F. Palumbo, CNR Institute of Nanotechnology NANOTEC, Italy
Correspondent: Click to Email
Plasma Enhanced Chemical Vapor Deposition Processes have been investigated by Riccardo d'Agostino and co-workers, and by many of his colleagues, in the late 80s and early 90s, mainly at low pressure, resulting in a large number of publications on the deposition kinetics and on the applications of coatings of different composition and properties. Many other PE-CVD approaches have been developed since then, and the deposition processes have been or are going to be deeply investigated, following the legacy of Riccardo d'Agostino in this field.

In this talk we present a set of data on the direct PE-CVD of nanometric capsules in the plasma phase resulting from Aerosol Assisted (AA) Atmospheric Pressure (AP) PE-CVD processes fed with Helium (carrier), Ethylene (film precursor) and aerosol droplets of solutions of drugs (nancomicyn, gentamicyn, etc). This approach [1, 2, 3] can lead, in certain conditions, to the deposition of thin coatings directly on the droplets of the aerosol, thus leading to the synthesis of drug-containing nanometric capsules, of potential interest for biomedical applications, e.g., as anti-bacterial surfaces [4].

The influence of various plasma parameters on the AA-AP-PE-CVD processes is discussed, as well as some properties of the coatings.

acknowledgements

The mentorship of Prof. d'Agostino is acknowledged by the authors of this contribution, as well as the recognition of his legacy in the field of plasma processing of materials.

references

1. A. Heyse et al, Plasma Proc. Polym. 8, 965 (2011)

2. Palumbo et al, Plasma Proc. Polym. 12, 1302 (2015)

3. Lo Porto et al, Polym. Chem. 8, 1746 (2017)

4. Sardella et al, Materials 2017, 9, 515