AVS 65th International Symposium & Exhibition
    Applied Surface Science Division Tuesday Sessions
       Session AS+BI-TuM

Invited Paper AS+BI-TuM1
Surface Analysis and Beyond, Using Ion Beams and Lasers

Tuesday, October 23, 2018, 8:00 am, Room 204

Session: Applied Surface Science: From Electrochemistry to Cell Imaging, a Celebration of the Career of Nicholas Winograd
Presenter: Nicholas Lockyer, University of Manchester, UK
Authors: N.P. Lockyer, University of Manchester, UK
J.C. Vickerman, University of Manchester, UK
Correspondent: Click to Email
Applications of secondary ion mass spectrometry (SIMS) have expanded enormously from pure surface science experiments to biology and bio-medicine, driven largely by developments in instrumentation. Polyatomic primary ion beams have resulted in a step-change in the technique's capability to detect and localise molecular chemistry, in biological cells and organic devices etc. This has stimulated new mass spectrometer designs and analytical paradigms for molecular imaging in 2D and 3D. The quest for still greater lateral resolution is a quest for improved sensitivity. Here ion beam chemistry can play a role, increasing the ionized fraction of the sputtered plume. Alternative routes to improved ionization and greater quantification include laser post-ionization. In this talk I will chart the progress made in these areas by our group in Manchester, and draw parallels with the work of the Winograd group, with whom we have had fruitful collaboration over many years.