AVS 59th Annual International Symposium and Exhibition
    Plasma Science and Technology Monday Sessions
       Session PS+BI-MoA

Paper PS+BI-MoA7
Localised, Non-Contact Surface Modification with Microplasma for Biotechnological Applications

Monday, October 29, 2012, 4:00 pm, Room 24

Session: Applications of (Multiphase) Atmospheric Plasmas (including Medicine and Biological Applications)
Presenter: S.A. Al-Bataineh, University of South Australia
Authors: S.A. Al-Bataineh, University of South Australia
E.J. Szili, University of South Australia
D.A. Steele, University of South Australia
N.H. Voelcker, University of South Australia
H.J. Griesser, University of South Australia
R.D. Short, University of South Australia
Correspondent: Click to Email

Localised surface modification of “open” surfaces is important for many biotechnological applications. In this study, we describe the utilisation of microcavity plasma arrays for localised surface modification of materials in a non-contact approach. In contrast to the current methods for localised surface modification, our method achieves spatially controlled surface modification without the use of a physical mask, photolithography or contacting the surface. Therefore, it provides the opportunity to reduce the number of modification steps and thus the cost of surface engineering processes. To this end, a 7 x 7 microcavity plasma array device (each cavity is separated by 500 µm and has a diameter of 250 µm with a depth of 55 nm) was manufactured and operated in helium at atmospheric pressure to generate, under optimised operating parameters, spatially separated modified regions on passivated surface coatings. The microplasma-patterned coatings were then used to control the spatial distribution of biomolecules such as proteins by allowing protein adsorption onto the modified regions whereas the rest of the coating remains non-fouling. Therefore, this approach resulted in spatially separated areas of immobilised protein. These surfaces were also used to control the spatial distribution of other biomolecules as well as living cells.