| AVS 64th International Symposium & Exhibition | |
| Biomaterial Interfaces Division | Wednesday Sessions |
| Session BI+AS-WeA |
| Session: | In Honor of Dave Castner's 65th Birthday: Multitechnique Bio-Surface Characterization II |
| Presenter: | Sally McArthur, Swinburne University of Technology and CSIRO, Australia |
| Authors: | S.L. McArthur, Swinburne University of Technology and CSIRO, Australia M. Abrigo, Swinburne University of Technology, Australia H. Askew, Swinburne University of Technology, Australia K.L. Jarvis, Swinburne University of Technology, Australia |
| Correspondent: | Click to Email |
Control and the ability to elicit specific responses from a biological system lies at the heart of most bioengineering. We want to immobilize proteins on biosensors but ask them to behave as they would in the body, stimulate cells to assemble tissues, form new blood vessels and replicate structures in the lab just as well as they can in our bodies. We want methods that prevent bacteria forming biofilms and better still we would like them to stop attaching to surfaces full stop. We have an armada of techniques at our disposal, surface engineering, macro, micro and nanomaterials, drugs and biomolecules, light, electricity and a plethora of analysis tools to give us new insight into how the systems we build behave. But as we increase the complexity of the system, we need to be able to match this with combinations of characterisation techniques that probe both the biological and physicochemical processes occurring at the biointerface.
This talk will explore how we utilise QCM, XPS, ToF-SIMS, florescence imaging and biological assays to investigate the influence of surface chemistry and micro and nanoscale topography on interactions with lipid vesicles and bacteria.