AVS 66th International Symposium & Exhibition
    Nanometer-scale Science and Technology Division Wednesday Sessions
       Session NS+2D+AS-WeA

Invited Paper NS+2D+AS-WeA3
Adding the Chemical Dimension to Lithography at All Scales: Enabling Cellular Therapies & Other Adventures in Biology and Medicine

Wednesday, October 23, 2019, 3:00 pm, Room A222

Session: Probing and Modifying Surface and Interfacial Chemistry at the Nanoscale
Presenter: Paul S. Weiss, University of California, Los Angeles
Correspondent: Click to Email
By controlling the exposed chemical functionality of materials from the submolecular through the centimeter scales, we have enabled new capabilities in biology, medicine, and other areas. I will discuss current and upcoming advances and will pose the challenges that lie ahead in creating, developing, and applying new tools using these capabilities. These advances include using biomolecular recognition in sensor arrays to probe dynamic chemistry in the brain and microbiome systems. In other areas, we introduce biomolecular payloads into cells for gene editing at high throughput for off-the-shelf solutions targeting hemoglobinopathies, immune diseases, and cancers. These methods use specific chemical functionalization and control of surface contact and adhesion in microfluidic channels.