| AVS 66th International Symposium & Exhibition | |
| Biomaterial Interfaces Division | Tuesday Sessions |
| Session BI-TuP |
| Session: | Biomaterial Interfaces Posters/Flash Session |
| Presenter: | Thuvarakhan Gnanasampanthan, Ruhr University Bochum, Germany |
| Authors: | T. Gnanasampanthan, Ruhr University Bochum, Germany A. Rosenhahn, Ruhr-University Bochum, Germany |
| Correspondent: | Click to Email |
Marine biofouling, which describes the accumulation of animals, plants, and microorganisms on surfaces in the aqueous environment, causes tremendous economic and ecological concerns.[1][2] Since commonly used antifouling coatings were banned and restricted because of their toxicity, new non‑toxic alternatives must be developed and established.[3] Polyelectrolyte multilayers are widely applied when protein resistance[4] and antibacterial properties[5] are required and provide a suitable platform to test the antifouling capabilities of promising compounds such as alginic acid (AA)[6], chitosan (CH)[7] and polyethylenimine (PEI)[8]. The physicochemical and marine antifouling properties of chemically cross-linked alginic acid/chitosan- and alginic acid/polyethylenimine-multilayers where investigated with a focus on the influence of surface charge and film hydration. Surface plasmon resonance spectroscopy revealed that all multilayers exhibit high protein resistance. Both, positively and negatively terminated AA/PEI‑multilayers did not show any differences regarding the amount of irreversibly bound protein, neither for negatively charged nor for positively charged proteins. However, for the AA/CH‑coatings the charge of the terminating layer had an effect on the protein adsorption. Besides, the type of polymer within the multilayers had a strong influence on the protein resistance. Microfluidic diatom accumulation assays[9] demonstrated that all multilayers present relatively low diatom settlement and that especially for AA/PEI‑multilayers the charge of the terminating layer has a significant influence on the attachment.
References
[1] M. P. Schultz, Biofouling 2007, 23, 331.
[2] I. B. Beech, J. Sunner, Curr. Opin. Biotechnol. 2004, 15, 181.
[3] D. M. Yebra, S. Kiil, K. Dam-Johansen, Prog. Org. Coat. 2004, 50, 75.
[4] J. H. H. Bongaerts, J. J. Cooper-White, J. R. Stokes, Biomacromolecules 2009, 10, 1287.
[5] P.-H. Chua, K.-G. Neoh, E.-T. Kang, W. Wang, Biomaterials 2008, 29, 1412.
[6] Y. Li, J. Rodrigues, H. Tomás, Chemical Society reviews 2012, 41, 2193.
[7] O. Yemul, T. Imae, Colloid Polym Sci 2008, 286, 747.
[8] M. N.V. Ravi Kumar, React. Funct. Polym. 2000, 46, 1.
[9] K. A. Nolte, J. Schwarze, C. D. Beyer, O. Özcan, A. Rosenhahn, Biointerphases 2018, 13, 41007.