| AVS 66th International Symposium & Exhibition | |
| Biomaterial Interfaces Division | Tuesday Sessions |
| Session BI-TuP |
| Session: | Biomaterial Interfaces Posters/Flash Session |
| Presenter: | Cindy Denise Beyer, Ruhr-University Bochum, Germany |
| Authors: | C. Beyer, Ruhr-University Bochum, Germany M. Reback, Ruhr-University Bochum, Germany J.A. Finlay, Newcastle University, UK S. Gopal, Ruhr-University Bochum, Germany A.S. Clare, Newcastle University, UK L. Schäfer, Ruhr-University Bochum, Germany N. Metzler-Nolte, Ruhr-University Bochum, Germany A. Rosenhahn, Ruhr-University Bochum, Germany |
| Correspondent: | Click to Email |
Efficient fouling-release coatings frequently consist of a silicone network modified by additional chemical compounds that reduce adhesion of marine fouling organisms. We explored the fouling-release potential of several oligopeptide sequences and tested them as self-assembled monolayers. The design motif of the peptide sequences considered inherent properties such as conformation and hydrophilicity. Different sequences were synthesized, and well-hydrated peptide coatings were assembled. All surfaces were characterized with respect to their wettability, layer thickness, and surface structure by contact angle goniometry, spectroscopic ellipsometry, and FTIR-spectroscopy. Protein adsorption of fibrinogen and lysozyme was very low on the oligopeptide SAMs. The assembled monolayers show remarkable fouling-release behavior against Navicula perminuta which was tested in a microfluidic assay. Also, the settlement of zoospores of the green algae Ulva linza was investigated. Besides the good antifouling behavior, the inclusion of Aib and D amino acids helped to create peptides that were 100% resistant against enzymatic degradation by trypsin. Due to their diversity, easy synthesis and biocompatibility, peptides could be used as active, hydrophilic components in fouling-release technologies.