| AVS 65th International Symposium & Exhibition | |
| Biomaterial Interfaces Division | Tuesday Sessions |
| Session BI+AS+IPF+NS-TuA |
| Session: | IoT Session: Biofabrication, Bioanalytics, Biosensors and Diagnostics and Flash Networking Session |
| Presenter: | Shashank Gahlaut, Indian Institute of Technology Delhi, India |
| Authors: | S.K. Gahlaut, Indian Institute of Technology Delhi, India C. Sharan, Indian Institute of Technology Delhi, India J.P. Singh, Indian Institute of Technology Delhi, India |
| Correspondent: | Click to Email |
The detection of endogenous gases including H2S is of immense interest nowadays as it opens the way to predict some diseases as well as an early stage diagnosis. These three gasotransmitter (H2S, NO and CO) gaseous molecules transfer the information and give the signal for mainly cardiovascular diseases Therefore, its detection has crucial importance in bio-medical science. Here, we demonstrate H2S detection from living cells using silver nanorods arrays fabricated by glancing angle deposition method. Colorimetric and wettability properties of silver nanorods are being observed for the gaseous detection. We use the model organism E.coli to demonstrate the feasibility of the method for the determination of live and resistant strains of the bacteria. For the human cell, we have used Hela cell line for the same. For the simplicity and feasibility of the technique, Android based mobile app has been developed for the colorimetric detection. Data obtained in this study show the potency of the system to identify live/dead bacteria with or without antibiotic treatment and compared with the time-consuming standard plating method, it a simple and cost-effective method for the estimation of living and resistant microorganism. The performance of AgNRs as H2S gas sensor is investigated by its sensing ability of 5 ppm of gas with an exposure time of only 30 s. It has potential application in the area of antimicrobial resistance and bio-medical healthcare.