AVS 64th International Symposium & Exhibition
    Biomaterial Interfaces Division Wednesday Sessions
       Session BI+NS-WeM

Invited Paper BI+NS-WeM3
Plasma Surface Modification of 2D and 3D Constructs: Creating and Evaluating New Materials for Biomedical Applications

Wednesday, November 1, 2017, 8:40 am, Room 12

Session: Biomaterials and Nanomaterials Fabrication & In Honor of Dave Castner's 65th Birthday: Multitechnique Bio-Surface Characterization I
Presenter: Ellen Fisher, Colorado State University
Correspondent: Click to Email
Plasma processing represents a powerful approach to modification of 2D and 3D substrates with an array of chemistries appropriate for use in biomedical applications. It is an attractive methodology because of its versatility, low waste, and scalability. The three major plasma surface modification classifications are deposition (film formation, polymerization), etching (removal of material) and functional group implantation (covalent bonding of chemical functional groups), which collectively provide a large landscape for creating materials with specific properties tailored for particular applications. Combining a range of spectroscopic techniques, materials characterization tools, and basic biological interaction studies provides a platform for deeper insight into these underlying mechanisms than just one approach alone. Yet, this can also lead to a range of obstacles, especially when seeking to apply traditional diagnostic methodologies to new systems and materials. For example, data on the surface chemistry of 3D constructs coated with thin films having a range of film chemistries (via utilization of allylamine/allylalcohol mixed gas plasmas) combined with an understanding of the gas-phase chemistry in these systems and cell-surfaces interaction studies highlights key properties required to tune the surface chemistries that can promote or deter cell viability and proliferation. Thus, this presentation will highlight a few key examples, including inherent challenges, where such a unified, comprehensive approach has been fruitful for 2D and 3D materials intended for use as antimicrobial materials, in separations, and for tissue engineering applications.