| AVS 63rd International Symposium & Exhibition | |
| Biomaterial Interfaces | Tuesday Sessions |
| Session BI+PB-TuP |
| Session: | Biomaterial Interfaces Poster Session (preceded by Oral Flash Presentations) |
| Presenter: | Jinn P. Chu, National Taiwan University of Science and Technology, Taiwan, Republic of China |
| Authors: | G.H. Jiang, National Taiwan University of Science and Technology, Taiwan, Republic of China C.C. Yu, National Taiwan University of Science and Technology, Taiwan, Republic of China C.L. Li, National Taiwan University of Science and Technology, Taiwan, Republic of China Y. Tanatsugu, National Taiwan University of Science and Technology, Taiwan, Republic of China J.P. Chu, National Taiwan University of Science and Technology, Taiwan, Republic of China M.J. Chen, Mackay Memorial Hospital Tamsui Campus, Taiwan, Republic of China S.H. Chang, Mackay Memorial Hospital Tamsui Campus, Taiwan, Republic of China |
| Correspondent: | Click to Email |
This presentation reports on the use of Zr-based (Zr53Cu33Al9Ta5) thin film metallic glass (TFMG) for the coating of various medical devices and compares the results with those obtained using conventional titanium nitride and pure titanium coatings . TFMG was selected as the coating material for its unique properties such as good biocompatibility and antibacterial property due to its amorphous atomic structure, revealing a great potential for biomedical applications. The TFMG coating was shown to reduce insertion forces and retraction forces by up to over seventy percent when tested using polyurethane rubber block. The benefits of TFMG-coated needles were also seen when tested using pig muscle tissues. Based on the nano-scratch test, the TFMG coatings achieved a low coefficient of friction (COF), about one order of magnitude lower than those of bare surface and other coatings. Furthermore, the adhesions of cancer cells and platelets to coatings are also examined. TFMG coating is shown to appreciably minimize the attachment of cancer cells and platelets by more than eighty percent in relative to those of Ti coating and bare surface. The low COF and non-stick coated surfaces by TFMG can be attributed to the absence of grain boundaries in the TFMG coating, smooth surface and low surface free energy.