| AVS 62nd International Symposium & Exhibition | |
| Surface Modification of Materials by Plasmas for Medical Purposes Focus Topic | Thursday Sessions |
| Session SM+AS+BI+PS-ThM |
| Session: | Plasma Processing of Biomaterials |
| Presenter: | Chia-Chi Yu, National Taiwan University of Science and Technology, Taiwan, Republic of China |
| Authors: | C. Yu, National Taiwan University of Science and Technology, Taiwan, Republic of China Y. Tanatsugu, National Taiwan University of Science and Technology, Taiwan, Republic of China S. Chyntara, National Taiwan University of Science and Technology, Taiwan, Republic of China C.M. Lee, National Taiwan University of Science and Technology, Taiwan, Republic of China W. Diyatmika, National Taiwan University of Science and Technology, Taiwan, Republic of China J.P. Chu, National Taiwan University of Science and Technology, Taiwan, Republic of China M.J. Chen, Mackay Memorial Hospital Tamsui Campus, Taiwan, Republic of China S.H. Chang, Mackay Memorial Hospital Tamsui Campus, Taiwan, Republic of China W.C. Huang, Mackay Memorial Hospital Tamsui Campus, Taiwan, Republic of China |
| Correspondent: | Click to Email |
Thin film metallic glasses (TFMGs) exhibit unique properties such as high strength, smooth surface as well as good wear- and corrosion-resistances due to their amorphous atomic structure. The biocompatibility and antibacterial property of TFMGs can also be obtained, which show great potential for biomedical applications. In addition, the low surface free energy of TFMGs in certain compositions can be achieved and leads to the relatively high hydrophobicity and the low friction coefficient.
In this presentation, various applications of TFMG are discussed, including the property enhancements of dermatome blade and syringe needle, thrombosis reduction for intravenous catheter, and the suppression of cancer cell attachments. A Zr-based TFMG is coated on substrates by using magnetron sputtering. The TFMG-coated dermatome blade show a great enhancement of durability and sharpness, compared with those of the bare one. For the syringe needle, significant reductions in insertion and retraction forces for TFMG-coated needle are achieved due to the non-sticky property and relatively low coefficient of friction. For thrombosis reduction, less platelet aggregations are observed on the TFMG than that on the bare glass in platelets adhesion test, suggesting TFMG-coated catheters is potentially useful to be placed into vessels for long periods of time with reduced numbers of the aggregation of blood platelets. For cancer cell attachment suppressions, TFMG exhibits the least cancer cell attachment among other control groups. Thus, anti-proliferation and anti-metastasis of medical tools can be achieved with TFMG coating.