AVS 61st International Symposium & Exhibition
    Biomaterials Plenary Session Sunday Sessions
       Session BP+BI+AS-SuA

Invited Paper BP+BI+AS-SuA5
Nanotechnology in the Pharmaceutical Sciences: From Lab to Industry

Sunday, November 9, 2014, 4:20 pm, Room 317

Session: Biomaterials Plenary Session
Presenter: Martyn Davies, The University of Nottingham and Molecular Profiles Ltd., UK
Correspondent: Click to Email
Surface and Interfacial phenomena influence the function and performance of many pharmaceutical and biomedical systems. This presentation will provide an insight into how the surface chemistry, morphology and bioactivity of novel drug delivery systems and biomedical materials may be probed at the nanoscale using a suite of complimentary advanced biophysical analytical techniques. The potential of such techniques for high-resolution imaging, the measurement of molecular and inter-particulate forces, biorecognition events and determining interfacial chemical structure will be explored for systems for gene delivery, inhalation therapy and tissue engineering scaffolds. The talk will encourage a comprehensive approach for the characterisation of complex pharmaceutical systems and will highlight the recent developments in high throughput surface analysis that provide an rapid screening strategy that has been shown to be valuable in understanding biological interactions at tissue engineering scaffold interfaces for stem cell applications. The successful translation of these methodologies and technologies into the commercial field through the spin-out Molecular Profiles Ltd will be discussed. The company has exploited surface and interfacial techniques in pharmaceutical research and development to help identify and resolve problems, in assisting in the design of novel delivery systems and in helping to understand the in-life performance of materials within complex pharmaceutical systems.