| AVS 61st International Symposium & Exhibition | |
| Biomaterial Interfaces | Tuesday Sessions |
| Session BI+AS+MN+NS-TuM |
| Session: | Biosensors |
| Presenter: | Paul Sheehan, Naval Research Laboratory |
| Authors: | P.E. Sheehan, Naval Research Laboratory S.C. Hernandez, National Research Council N. Long, Nova Research S.P. Mulvaney, Naval Research Laboratory J. Robinson, Naval Research Laboratory R. Stine, Nova Research C.R. Tamanaha, Naval Research Laboratory S.G. Walton, Naval Research Laboratory |
| Correspondent: | Click to Email |
Graphene has many properties that are highly suited for biological studies. For instance, its atomic thinness, high electrical conductivity, and simple production methods are ideal for biosensing. As another example, graphene can be attached to arbitrary substrates to lend them the chemical flexibility of carbon while adding only an ultrathin coating. For both biosensing and biofunctionalization, it is critical to produce high quality films that are precisely modified with the desired chemistry. For biosensing, the sensor must be functionalized for specific receptor-ligand recognition such as DNA-DNA or antibody-antigen binding. We will discuss our strategies for functionalization and the successful detection of specific DNA hybridization biologically-active field-effect transistors (BioFETs) based on chemically modified graphene. We will then discuss our use of graphene to interface biology with materials ranging from polymers to dielectrics to semiconductors. Graphene’s incredible thinness enables its inclusion in more traditional sensing platforms as a non-intrusive functionalization layer, discreetly lending its chemical flexibility to other, more inert materials without otherwise impacting the sensing device.