| AVS 58th Annual International Symposium and Exhibition | |
| Biomaterial Interfaces Division | Monday Sessions |
| Session BI-MoM |
| Session: | Biomolecules at Interfaces |
| Presenter: | Sally McArthur, Swinburne University of Technology, Australia |
| Authors: | R.V. Uljin, The University of Strathclyde, UK V. Jayawarna, The University of Strathclyde, UK S. Roy, The University of Strathclyde, UK M.J. Dalby, The University of Strathclyde, UK S.L. McArthur, Swinburne University of Technology, Australia |
| Correspondent: | Click to Email |
Peptides are highly versatile building blocks for the production of supramolecular gels which mimick certain properties of biological systems but with minimal complexity. These gels may be ideally suited to interface synthetic systems with biology, and as such have attracted much interest in a range of areas including health care and energy related technologies. We have developed versatile gelator systems based on aromatic peptide amphiphiles, which self-assemble via a unique mechanism involving π-interlocked β-sheets. These systems display highly tunable supramolecular functionalities, giving rise to materials with controlled mechanical properties, nanotopography and bioactive properties. We will show that these properties can be controlled by exploiting non-equilibrium self-assembly which may involve the use of biocatalysts to control the self-assembly process. We will discuss progress in fundamental understanding of these systems as well as applications as matrices for stem cell differentiation.
References:
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