AVS 57th International Symposium & Exhibition
    Marine Biofouling Topical Conference Monday Sessions
       Session MB+BI+AS-MoA

Paper MB+BI+AS-MoA3
Resistance of Saccharide-Terminated Alkylthiol Self-Assembled Monolayers to Protein Adsorption and Marine Biofouling

Monday, October 18, 2010, 2:40 pm, Room Navajo

Session: Preventing & Characterizing Marine Biofouling
Presenter: T. Ederth, Linköping University, Sweden
Authors: T. Ederth, Linköping University, Sweden
T. Fyrner, Linköping University, Sweden
T. Ekblad, Linköping University, Sweden
M. Hederos, Linköping University, Sweden
H.-H. Lee, Linköping University, Sweden
A. Mangone, Linköping University, Sweden
P. Konradsson, Linköping University, Sweden
C.-X. Du, Linköping University, Sweden
M.E. Pettitt, University of Birmingham, UK
M.E. Callow, University of Birmingham, UK
J.A. Callow, University of Birmingham, UK
S.L. Conlan, University of Newcastle, UK
A.S. Clare, University of Newcastle, UK
F. D'Souza, TNO Science and Industry, The Netherlands
G.T. Donnelly, TNO Science and Industry, The Netherlands
A. Bruin, TNO Science and Industry, The Netherlands
P.R. Willemsen, TNO Science and Industry, The Netherlands
B.G. Liedberg, Linköping University, Sweden
Correspondent: Click to Email

The protein resistance of galactoside-terminated alkanethiol self-assembled monolayers (SAMs) can be tuned by partial methylation of the terminating saccharides, and has a non-trivial dependence on the degree of methylation [1], and for other mono- and oligosaccharide-terminated SAMs, protein resistance may vary considerably with small changes in sugar structure. We have used such mono- and oligosaccharide-terminated SAMs in a series of assays using marine fouling organisms as biological model systems, representing common micro- and macrofoulers. We investigate to what extent protein resistance properties are related to effective prevention of fouling by the marine model organisms, and discuss the results in terms of physicochemical properties of the SAMs.

[1] Hederos, M.; Konradsson, P.; Liedberg, B., Langmuir 2005, 21(7), 2971-2980. DOI: 10.1021/la047203b