| AVS 56th International Symposium & Exhibition | |
| Biomaterial Interfaces | Thursday Sessions |
| Session BI-ThP |
| Session: | Biomaterial Interfaces Poster Session II (Arrays, Sensing, Micro/Nanofabrication, SPM) |
| Presenter: | B.S. Davis, Brigham Young University |
| Authors: | B.S. Davis, Brigham Young University H.J. Conley, Brigham Young University J.L. Knoebel, Brigham Young University K.B. Hurd, Brigham Young University J.N. Harb, Brigham Young University M.R. Linford, Brigham Young University R.C. Davis, Brigham Young University |
| Correspondent: | Click to Email |
We present a scanning probe lithography technique that allows for patterning of adsorbed, water-soluble polymers on functionalized oxide surfaces. SiO2 and borosilicate glass surfaces were functionalized with a negatively charged carboxyl-terminated silane monolayer. A ca. 2 nm poly-L-lysine layer was then deposited over the silane film. An atomic force microscope (AFM) probe was used to scribe away lines and areas of the positive poly-L-lysine layer, exposing the negatively charged silane underlayer. The AFM scribing experiments were performed both in air and in water. Regions were scribed and then backfilled with a fluorescently tagged polymer. Characterization of the scribing was done with tapping mode AFM. Optical fluorescence microscopy was used to image backfilled regions. AFM height and phase mode data showed lines and spaces with half pitch features as small as 12 nm created with a scribing force of 0.3 μN.