AVS 53rd International Symposium
    Surface Science Tuesday Sessions
       Session SS-TuP

Paper SS-TuP33
Enhanced Initial Hydrophilicity and Biological Response of Microstructured Titanium Implants by Chemical Modification

Tuesday, November 14, 2006, 6:00 pm, Room 3rd Floor Lobby

Session: Surface Science Poster Session
Presenter: M. De Wild, Institut Straumann AG Switzerland
Authors: M. De Wild, Institut Straumann AG Switzerland
F. Rupp, Poliklinik für Zahnaerztliche Prothetik Tuebingen Germany
L. Scheideler, Poliklinik für Zahnaerztliche Prothetik Tuebingen Germany
M. Wieland, Institut Straumann AG Switzerland
J. Geis-Gerstorfer, Poliklinik für Zahnaerztliche Prothetik Tuebingen Germany
G. Zhao, Georgia Institute of Technology
Z. Schwartz, Georgia Institute of Technology
D. Cochran, University of Texas Health Science Center at San Antonio
B.D. Boyan, Georgia Institute of Technology
Correspondent: Click to Email
Surface topography and chemistry both influence initial wettability and peri-implant bone apposition of implants. Until now, sandblasted and acid etched (SLA) titanium surfaces are initially hydrophobic due to microstructuring and contamination with hydrocarbons and carbonates. The purpose of this study was to investigate initial hydrophilicity and protein adsorption and examine its role in the response of osteoblasts on a new developed chemically modified implant surface called SLActiv. By chemical modification it is now possible to overcome the initial hydrophobic behavior of standard implant surfaces. The innovative clean-room production method influences protein/surface and cell/surface interactions in vitro. This study shows that surface energy controls osteoblast differentiation and local factor production. Histological and biomechanical observations of osseointegration approve the enhanced interactions between the SLActive implant surface and the tissue in the initial healing phase.