AVS 53rd International Symposium
    Biomaterial Interfaces Tuesday Sessions
       Session BI2-TuM

Paper BI2-TuM11
Partial Hydrolysis of a Polyimide Surface for Biomolecule Immobilization and Biosensing

Tuesday, November 14, 2006, 11:20 am, Room 2014

Session: Biodiagnostic Innovation
Presenter: S. Chakraborty, Illinois Institute of Technology
Authors: S. Chakraborty, Illinois Institute of Technology
P. Betala, Illinois Institute of Technology
W.J. Buttner, Illinois Institute of Technology
V.H. Perez-Luna, Illinois Institute of Technology
J.R. Stetter, Illinois Institute of Technology
Correspondent: Click to Email
The unique electrical, thermal, chemical and mechanical properties of polyimide films make them widely used in electronic components. Thus, their surface modification could be of interest in the biosensors field. Here we present a detailed study on the surface modification of polyimide films through partial hydrolysis. The surface modification is explored by wettability measurements and Fourier Transform Infrared (FTIR) Spectroscopy. Strategies to immobilize biomolecules such as antibodies on these surfaces are presented. Immobilization strategies take advantage of the carboxyl groups formed during the hydrolysis procedure. The application of this process to biosensing is illustrated with an impedance based imaging system array that is adapted to the detection of biological entities.