AVS 51st International Symposium
    Magnetic Interfaces and Nanostructures Tuesday Sessions
       Session MI-TuA

Invited Paper MI-TuA7
Advances in MR Elastic Displacement Imaging and Non-invasive Measurements of Myocardial Compliance

Tuesday, November 16, 2004, 3:20 pm, Room 304A

Session: BioMagnetism
Presenter: H. Wen, NHLBI/NIH
Correspondent: Click to Email

The vector nature of the NMR signal gives rise to a group of displacement imaging methods in magnetic resonance imaging that are based on spin phase-shifts. They are suited for studying physiological motions such as the heartbeat and elastic reponses of arterial walls to the blood pressure. Elevated myocardial stiffness is a cause of high diastolic blood pressure and congestive heart failure. The traditional measure of heart chamber stiffness uses diagnostic catheterization, an invasive procedure not acceptable for many patients. MR elastic displacement imaging is a new way to estimate material viscoelastic parameters non-invasively. It has been validated in animal models and shown feasible in humans. Clinical trials to detect heart and artery stiffening in patients with congenital heart disease are being prepared.