IUVSTA 15th International Vacuum Congress (IVC-15), AVS 48th International Symposium (AVS-48), 11th International Conference on Solid Surfaces (ICSS-11)
    Biomaterials Thursday Sessions
       Session BI-ThM

Invited Paper BI-ThM9
Design of Bioadhesive Polymers for Use at Mucosal Interfaces

Thursday, November 1, 2001, 11:00 am, Room 102

Session: Protein Surface Interaction
Presenter: A. Hoffman, University of Washington
Correspondent: Click to Email
Mucosal surfaces of the body include "wet" surfaces such as the eye, nose, mouth, GI-tract, vagina and lungs. They represent a large surface area of the body and thus may be an attractive route for delivery of drugs. When a drug formulation is applied to those surfaces, it may resist being washed away due to a combination of its own viscosity plus its intermolecular interactions with the mucous polymer coating. Two typical bioadhesive polymers that have been most often applied for mucosal drug delivery are polyacrylic acid and chitosan. This talk will describe drug delivery formulations containing PAA or chitosan or their derivatives that may provide better control over drug release rate and duration.