IUVSTA 15th International Vacuum Congress (IVC-15), AVS 48th International Symposium (AVS-48), 11th International Conference on Solid Surfaces (ICSS-11)
    Biomaterials Monday Sessions
       Session BI-MoP

Paper BI-MoP11
Piezoresistive Microcantilever Sensors for the Detection of Biological Molecules

Monday, October 29, 2001, 5:30 pm, Room 134/135

Session: Biorecognition Poster Session
Presenter: T.L. Porter, Northern Arizona University
Authors: T.L. Porter, Northern Arizona University
M.P. Eastman, Northern Arizona University
D.L. Pace, Northern Arizona University
T.R. Dillingham, Northern Arizona University
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Microsensors capable of recognizing single biological molecules have been fabricated using piezoresistive microcantilever technology. Using 25 base single strand DNA layers as the active sensing material, small piezoresistive microcantilevers in contact with this surface were able to recognize the presence of the complimentary strand, while ingoring the presence of strands differing by 2-5 base units. The analyte recognition is by means of a simple resistance change in the microcantilever, meaning only simple, inexpensive electronics are required for this device. Several sensors may be grouped together to form small bio-sensing arrays.