Molecular wires, molecular interconnect structures, molecular emission devices and, indeed, much of molecular electronics requires efficient control of charge transport processes at the molecule/electrode interface. Direct measurements on individual molecular transport junctions are beginning to appear, and will be featured in this symposium. Understanding the conductance properties of molecular junctions requires a computational model that deals effectively with both the continuum (electrode) and discrete (molecular) aspects of the issue. The problem is similar to that of chemisorption, and the Hamiltonian models discussed are also similar. Because of this discrete/continuum coupling, the molecular levels are shifted and broadened. This leads to self energies that describe the effective state densities for injection and transport. The use of Landauer type expressions then leads to specific predictions for voltage dependence conductance in the coherent regime; most measures of individual junctions reported to date indeed can be characterized in this way. For actual injection and dissipative charge transport, the Landauer model is no longer appropriate. Here considerations of typical molecular behavior arise, and at least five different charge transport mechanisms can be posited. We will discuss some aspects of these mechanisms, advantages and disadvantages for long range charge transport in molecular wires, aspects of the energy dissipation problem and the energetic control of transport by design both of the molecule itself and of the interface.