AVS 46th International Symposium
    Biomaterial Interfaces Group Wednesday Sessions
       Session BI-WeP

Paper BI-WeP8
Observation of Metal Clusters on Pancreatic Cells by Lateral Force Microscopy

Wednesday, October 27, 1999, 5:30 pm, Room 4C

Session: Poster Session
Presenter: A. Cricenti, Consiglio Nazionale Delle Ricerche, ITALY
Authors: A. Cricenti, Consiglio Nazionale Delle Ricerche, ITALY
R. Generosi, Consiglio Nazionale delle Ricerche, Italy
S. Cotesta, Consiglio Nazionale delle Ricerche, Italy
M. Girasole, Consiglio Nazionale delle Ricerche, Italy
P. Perfetti, Consiglio Nazionale delle Ricerche, Italy
A. Congiu-Castellano, Universita' di Roma La Sapienza, Italy
Correspondent: Click to Email
The interaction between pancreatic cells and metal ions have been studied at membrane level by Atomic/Lateral Force Microscopy in the repulsive regime of contact mode. The atomic force microscope can give both topographic and chemical (in lateral friction mode) informations on the cellular membrane of cells. Morphological characteristics of non infected cells and metal infected cells were easily imaged from fixed and dried cell preparations. Upon Cd2 and Zn ions uptake, the pancreatic cells don't change their morphology but the lateral friction images localized several metal clusters on the cellular membrane.