AVS 46th International Symposium
    Biomaterial Interfaces Group Wednesday Sessions
       Session BI-WeM

Paper BI-WeM6
Biomaterials That Talk

Wednesday, October 27, 1999, 10:00 am, Room 613/614

Session: Cell Solid-Surface Interactions
Presenter: P.S. Stayton, University of Washington
Authors: P.S. Stayton, University of Washington
T.C. McDevitt, University of Washington
K.E. Nelson, University of Washington
C.M. Giachelli, University of Washington
R.B. Vernon, Hope Heart Institute
H. Sage, Hope Heart Institute
D.G. Castner, University of Washington
Correspondent: Click to Email
We are working to develop a variety of biomaterials that are designed to communicate with biomolecules, cells, and tissues. This goal requires complementary surface assembly techniques, engineering of biomolecules designed for surface applications, and detailed characterization of the biomolecules at surfaces. In this talk, I will present joint protein engineering and microfabrication approaches to constructing coatings that control cell phenotype in confined dimensions on device surfaces. These coatings are designed to interact with specific receptors to control cell motility, proliferation, and protect against apoptosis.