AVS 46th International Symposium
    Biomaterial Interfaces Group Tuesday Sessions
       Session BI-TuM

Paper BI-TuM8
Molecular Orientation Distributions in Submonolayer Films Corresponding to Quasi-Reversible Electron Transfer Behavior

Tuesday, October 26, 1999, 10:40 am, Room 613/614

Session: Protein Solid-Surface Interactions II
Presenter: R.T. Robertson, University of Arizona
Authors: S.S. Saavedra, University of Arizona
R.T. Robertson, University of Arizona
N.R. Armstrong, University of Arizona
S. Mendes, University of Arizona
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The relationship between the molecular orientation distribution and the electron transfer behavior of immobilized redox proteins has been investigated through the use of novel waveguide-based spectroelectrochemical methods. The ability to probe the electron transfer behavior which corresponds to a particular molecular orientation will provide significant insight into the fundamental electron transfer processes that occur in physiological systems. The orientation geometry is obtained using an electroactive integrated optical waveguide (EA-IOW) format coupled with electroactive total internal reflection fluorescence (EA-TIRF). Orientation distributions of horse heart cytochrome c corresponding to quasi-reversible electron transfer have been characterized and will be discussed here.