| Pacific Rim Symposium on Surfaces, Coatings and Interfaces (PacSurf 2018) | |
| Biomaterial Surfaces & Interfaces | Wednesday Sessions |
| Session BI-WeM |
| Session: | Soft Surfaces and Biofunctional Coatings |
| Presenter: | Mildred Quintana, Universidad Autónoma de San Luis Potosí, México |
| Correspondent: | Click to Email |
The unique combination of properties of carbon nanostructures, such as high specific surface area, chemical stability, mechanical strength, flexibility, high electrical and thermal conductivity, and tunable band gap and shape, make them ideal materials for the development of a number of bio-applications including biosensors [1], photodynamic therapy agents [2], and active surfaces for cellular growth [3]. However, for applicability several problems arise, including scalability, dispersibility, stability, and reproducibility. Several authors have proposed chemical functionalization as a feasible solution to render carbon nanostructures dispersible in many solvents, comprising water, and readily for its integration in hybrids materials [4]. Furthermore, by performing chemical organic reactions on carbon nanostructures, it is possible to exactly adjust the interfacial properties to increase biocompatibility [5] or to prompt lipid membrane translocation [6]. In this work, I will describe our recent efforts on the chemical functionalization of carbon nanotubes and graphene towards the development of SERS biosensors, photodynamic therapy agents and active surfaces for cellular growth. The importance of the tailored design of the chemical surface of the nanostructure for the desired application will be extensively discussed.
References
1. D. Hernández-Sánchez, G. Villabona-Leal, I. Saucedo-Orozco, V. Bracamonte, E. Pérez, C. Bittencourt, M. Quintana. (2018): Stable graphene oxide–gold nanoparticle platforms for biosensing applications. Phy.Chem.Chem. Phy., 20, 1685.
2. D. Hernández-Sánchez, M. Scardamaglia, S. Saucedo-Anaya, C. Bittencourt, M. Quintana. (2016): Exfoliation of Graphite and Graphite Oxide in Water by Chlorine e 6 . RCS Adv. 6, 66634-66640.
3. G. Cellot, F. M. Toma, Z. Kasap, J. Lahisram, A. Villari, M. Quintana, S. Cipollone, M. Prato, Laura Ballerini. (2011): Carbon Nanotube Scaffolds Tune Synaptic Strength in Cultured Neural Circuits: Novel Frontiers in Nanomaterial-Tissue Interactions. J. Neurosci. 7, 12945–12953.
4. M. Quintana, E. Vázquez, M. Prato. (2013): Organic Functionalization of Graphene in Dispersions. Acc. Chem. Res. 46, 138-148.
5. Micoli, A. Turco, E. Araujo-Palomo, A. Encinas, M. Quintana, M. Prato. (2014): Supramolecular Assemblies of Nucleoside Functionalized Carbon Nanobutes: Synthesis, Film Preparation and Properties. Chem. Eur. J. 20, 5397-5402.
6. V. Pérez-Luna, C. Moreno-Aguilar, J.L. Arauz-Lara, S. Aranda-Espinoza, M. Quintana. (2018): Interaction of Functionalized Multi-Walled Carbon Nanotubes with Giant Phospholipid Vesicles as Model Cellular Membrane System. In revision.