| Pacific Rim Symposium on Surfaces, Coatings and Interfaces (PacSurf 2016) | |
| Nanomaterials | Tuesday Sessions |
| Session NM-TuP |
| Session: | Nanomaterials Poster Session |
| Presenter: | Jaime Santoyo-Salazar, Nanosciences and nanotechnology, CINVESTAV-IPN, México |
| Authors: | A.L. Ramírez-Núñez, Doctoral Program in Nanosciences and Nanotechnology CINVESTAV-IPN, Mexico J. Santoyo-Salazar, Nanosciences and nanotechnology, CINVESTAV-IPN, México L.F. Jiménez-García, Faculty of Sciences, UNAM, México G. Goya Rossetti, Instituto de Nanociencia de Aragón, Spain |
| Correspondent: | Click to Email |
Recently biosynthetic methods employing either biological entities or plant extracts have emerged as an easy, fast and economical alternative to chemical and physical síntesis procedures for the production of safer nanomaterials for human use. An eco-friendly semi-green method was used in order to obtain magnetite magnetic nanoparticles (Fe3O4-MNPs). Besides the know effect of polyphenols as therapeutical agents in cancer diseases, biomolecules from aqueous extracts can act as capping and reducing agents wich effectively replace toxic chemical reductans. Plant extracts with a rich mixture of active biological phytochemicals (i.e. polyphenol compounds, tannins, saponnins, flavonoids) control and shape the growing nanoparticles. Superparamagnetic properties have been studied extensively due to their potential use in hyperthermia in cancer treatment. The green synthesis of Fe3O4-MNPs with aqueous extracts represent a major advantage in the synthesis of superparamagnetic materials for biomedical usage, due to their diminished toxicity to biological organisms and more efficient drug delivery carriers for specific cancer diseases. In order to explore the diversity of biomolecules in the obtention of Fe3O4-MNPs, in this work an aqueous extract from Cinnamomun verum and Vanilla planifolia (natural pods and synthetic extract) were used during the synthesis of magnetite.
The Fe3O4 MNPs obtained were identified by XRD (PDF-19-0629) corresponding to an inverse spatial group Fd3m (227) inverse spinel FCC structure, a= 8.355 Å in synthetic vanilla and a=8.362 Å in vanilla pods extract (V. planifolia), and a=8.366 Å in C. verum. IR peaks at 576 cm-1 correspond to Fe-O bonding formation; vibrational peaks at 576-1641 and 3415 cm-1 suggest phenol molecules involved in bio-reduction process. XRD and HRTEM diffraction patterns overlap with the corresponding Fe3O4 peaks (220),(311),(400),(511),(440). The d spacing 2.4 Å in V. planifolia and 2.7 Å in C. verum match the main diffraction plane 35° (311). The particle size calculated by Scherrer´s equation by Scherrer´s equation (t=Kl/b cos Ɵ) in V. planifolia was 12 nm and 14 nm in C. verum. AFM-MFM data show a monodomain arrangement of 2-3 nm in V. planifolia and 5-6 nm in C. verum. VSM data indicate that magnetization increases rather using C. verum extract (64.89 emu/g) than V. planifolia (46.6 emu/g). The SPA values suggest that vanilla pods extract has an advantageous performance during Fe3O4-MNPs synthesis due to their increased heating capability (64.51 W/g). The bio-synthesis of Fe3O4 MNPs obtained by aqueous plant extracts are commensurable to those obtained by a chemical method with a better performance than synthetic extract.
References.
[1] G. Canizal, P. Schabes-Retchkiman. Mater. Chem. Phys. 97 (2006) 321.
[2] R. Herrera, J.L. Rius, C. App. Phys. A 100 (2010) 453.
[3] G. Rosano-Ortega, P. Schabes-Retchkiman. American ScienIfic Publishers 6 (2006) 1.
[4]J.Chomoucka,J.Drbohlavova,D.Huska.PharmacologicalResearch62(2010)144.
[5] A. Ito, H. Honda, T. Kobayashi. Cancer Immunol Immunother 55 (2006) 320.
[6] N. Anton, J.P. Benoit, P. Saulnier. Journal of Controlled Release 128 (2008) 185.
[7] J. Santoyo-Salazar, L. Perez, O. de Abril. Chem Mat. 23 (2011) 1379.
[8] J. Santoyo-Salazar, M.A. Castellanos. J. Scanning Probe Microscopy 4 (2009) 17.
[9] Goya, G.F. ; Grazu, V.; Ibarra, M.R. Current Nanoscience 4(2008) 1.