| Pacific Rim Symposium on Surfaces, Coatings and Interfaces (PacSurf 2016) | |
| Nanomaterials | Tuesday Sessions |
| Session NM-TuM |
| Session: | Nanofabrication and Nanodevices I |
| Presenter: | Enrique Samano, Universidad Nacional Autónoma de México, México |
| Authors: | E.C. Samano, Universidad Nacional Autónoma de México, México T.H. LaBean, North Carolina Central University, USA |
| Correspondent: | Click to Email |
Artificial DNA nanostructures such as DNA origami have garnered significant interest as templates for sub-20 nm assembly of materials because their design allows for the incorporation of binding sites to assemble nanocomponents with 6nm resolution. The DNA origami strategy for assembling designed supramolecular complexes requires ssDNA as a scaffold strand. A system is described that was designed using approximately one third of the M13 bacteriophage genome as a scaffold. Folding of the short 2404-base ssDNA scaffold into a variety of two-dimensional origami shapes (rectangle, triangle, and circle) with high assembly yields is demonstrated. DNA origami templates, modified to have DNA binding sites with a uniquely coded sequence, can be used to produce complex metallic nanostructures of programmable design. Gold nanoparticles functionalized with a complementary DNA sequence were attached to specific binding sites on the scaffold in a highly controllable manner to form a predesigned metallic array on two nanostructures.