Paper BI-MoE5
Multifunctional Bionanotubular Implant Surfaces

Monday, December 12, 2016, 7:00 pm, Room Milo

Bionanotubular surfaces offer exciting progress toward the design of multifunctional medical implants. To bring this to reality, we have synthesized and optimized the mechanical, physical, biocompatibility, and interfacial properties of titania nanotube surfaces using in-situ TEM, SEM, FIB, FTIR, and WCA measurements. We have observed that the fabrication of bionanotubular titania surfaces with elastic modulus close to actual bone promotes osteoblast growth and prevents stress shielding. In addition, bionanotubular titania surfaces could be considered a suitable alternative route for the development of drug-eluting and antimicrobial implants due to the fact that these nanostructures are not an added coating but rather are rooted in the implants and will not delaminate from the surface. Such drug-eluting implants can prevent unnecessary side effects caused by oral administration of drugs, increase drug efficiency, and prevent infection related implant complications and failures.