AVS 64th International Symposium & Exhibition
    MEMS and NEMS Group Monday Sessions
       Session MN+BI+NS-MoM

Paper MN+BI+NS-MoM5
Micro-Gas Chromatography Linked with Nano-optomechanical Systems for Breath Analysis

Monday, October 30, 2017, 9:40 am, Room 24

Session: Feature Session: Large Scale Integration of Nanosensors
Presenter: Khulud Almutairi, University of Alberta, Canada
Authors: K. Almutairi, University of Alberta, Canada
W.K. Hiebert, National Institute for Nanotechnology, Canada
Correspondent: Click to Email

One of the applications of microfabrication and nanofabrication technologies is fabricating a micro-Gas Chromatography (GC) on a chip. The miniaturized GC system is designed for the rapid determination of volatile organic compounds (VOCs) that can be used in remote locations with low consumptions and cost of utilization. It was reported that specific VOCs can be found in exhaled breath sample from patients suffering from lung cancer [1]. Therefore, designing a μGC device can help in separating and analyzing VOCs that comes from exhaled breath samples, such as acetone, benzene and toluene.

Our group has reported that connecting Nano-optomechanical systems (NOMS) to Gas Chromatography can enhance the detection sensitivity limit of VOCs up to 1 ppb [2]. This presentation will feature our first efforts in connecting μGC with NOMS for higher sensitivity and responsivity. In particular, we will discuss our NOMS sensor chips with microheaters for localized control of sensor temperature. One of our goals is to move toward large scale integration of GC analysis by simultaneously sensing at multiple temperatures.

REFERENCES:

[1] Mazzone, Peter J. "Exhaled breath volatile organic compound biomarkers in lung cancer." Journal of breath research 6, no. 2 (2012): 027106.

[2] Venkatasubramanian, Anandram, Vincent TK Sauer, Swapan K. Roy, Mike Xia, David S. Wishart, and Wayne K. Hiebert. "Nano-optomechanical systems for gas chromatography." Nano Letters 16, no. 11 (2016): 6975-6981.