| AVS 62nd International Symposium & Exhibition | |
| Biomaterial Interfaces | Tuesday Sessions |
| Session BI-TuA |
| Session: | Cells and Microorganisms at Surfaces |
| Presenter: | YingChih Chang, Academia Sinica, Taiwan, Republic of China |
| Authors: | Y.C. Chang, Academia Sinica, Taiwan, Republic of China P.Y. Yeh, Academia Sinica, Taiwan, Republic of China |
| Correspondent: | Click to Email |
A series of biomimetic polypeptide layer-by-layer conjugated supported lipid bilayers as lubricated thin films were constructed and characterized for their physical properties under cell-surface contact. The construct was used to promote the selection and maintenance of stem/progenitor cell colonies from the primary culture in one example, and to isolate circulating epithelial cells from human peripheral blood in another example. The adsorption of serum proteins, and nonspecifically bound cells are clearly reduced when a lipid coating was employed as the underneath layer, as studied by quartz-crystal microbalance with dissipation, and immunohistochemistry.