| AVS 62nd International Symposium & Exhibition | |
| Applied Surface Science | Tuesday Sessions |
| Session AS+BI-TuA |
| Session: | Challenges in the Characterization of Polymer/Organic/ Biological Systems |
| Presenter: | Zihua Zhu, Pacific Northwest National Laboratory |
| Authors: | Z. Zhu, Pacific Northwest National Laboratory Y. Zhou, Pacific Northwest National Laboratory X. Hua, Pacific Northwest National Laboratory J. Yu, Pacific Northwest National Laboratory J.E. Evans, Pacific Northwest National Laboratory D. Lao, Pacific Northwest National Laboratory X.-Y. Yu, Pacific Northwest National Laboratory |
| Correspondent: | Click to Email |
In situ liquid SIMS is an R&D 100 award winner that was developed in PNNL since 2010. System for analysis at the liquid vacuum interface (SALVI) coupled with liquid SIMS has proven to be a promising new tool to provide molecular information at solid/liquid interfaces.[1,2] However, our initial data showed that signals of secondary positive ions were too low to be usable in some cases.[2,3] In addition, it was difficult to obtain strong negative molecular ion signals with m/z > 100.[2] These two drawbacks make SIMS community wonder the potential applications of this new analytical approach. In this presentation, we report that strong positive and negative molecular signals are achievable after we optimize the SIMS experimental conditions. Our results show that both beam current and primary ion species (e.g., Bi+, Bi3+, Bi32+) play important roles in achieving optimal molecular signals at the liquid interface. Data sets from three model systems, including an ionic liquid, water, and several liposome solutions, will be presented. In addition, beam damage at the liquid surface will also be discussed.
[1] B. Liu, X. Y. Yu, Z. Zhu, X. Hua, L. Yang, Z. Wang, Lab Chip, 2014, 14, 855.
[2] X. Hua, X. Y. Yu, Z. Wang, L. Yang, B. Liu, Z. Zhu, A. E. Tucker, W. B. Chrisler, E. A. Hill, S. Thevuthasan, Y. Lin, S. Liu, and M. J. Marshall, Analyst, 2014, 139, 1609.
[3] L. Yang, Z. Zhu, X. Y. Yu, S. Thevuthasan, J. P. Cowin, Anal. Methods,2013, 5, 2515.