AVS 60th International Symposium and Exhibition | |
Biomaterial Interfaces | Thursday Sessions |
Session BI+AS+BA+NS+SS-ThA |
Session: | Biomolecules at Interfaces |
Presenter: | M. Walker, National Institute of Standards and Technology (NIST) |
Authors: | M. Walker, National Institute of Standards and Technology (NIST) A. Vaish, National Institute of Standards and Technology (NIST) and Institute of Bioscience and Biotechnology Research D. Vanderah, National Institute of Standards and Technology (NIST) and Institute of Bioscience and Biotechnology Research |
Correspondent: | Click to Email |
Spectroscopic ellipsometry was used to evaluate the resistance to protein adsorption of self-assembled monolayers (SAMs) of HS(CH2)3O(CH2CH2O)6M and [HS(CH2)3]2CHO-(CH2CH2O)6M, where M = CH3 or H, on Au. The SAMs were exposed to fibrinogen, a soluble protein frequently used to evaluate surface protein resistance properties, and rhodopsin, an integral membrane protein. We show that the that the nature of the oligo(ethylene oxide) end group governs the extent of protein adsorption resistance of OEO SAMS to integral membrane proteins.