| AVS 60th International Symposium and Exhibition | |
| Biomaterial Interfaces | Monday Sessions |
| Session BI+AI+BA+IS-MoA |
| Session: | Biofouling |
| Presenter: | S. Bauer, University of Heidelberg, Germany |
| Authors: | S. Bauer, University of Heidelberg, Germany J. Finlay, University of Birmingham, UK M.E. Callow, University of Birmingham, UK J.A. Callow, University of Birmingham, UK A. Rosenhahn, Ruhr-University Bochum, Germany |
| Correspondent: | Click to Email |
Zwitterionic surfaces are a class of coatings that receive increasing attention due to their good antifouling performance.1 Since early work on protein resistance of mixed, charged self-assembled monolayers (SAMs), charge neutrality seems to be a prerequisite for their inert properties. 2,3 Similar to established non-fouling ethylene glycol chemistries, zwitterionic systems rely on a strong hydration of the coating. In this study we attempt a systematic analysis to which extend charge neutrality and the chemical nature of the charged groups affect their antifouling performance. Positively charged trimethylammonium terminated thiols were therefore mixed with sulfonate-, carboxylate- and phosphonate-terminated undecanethiols in varying ratios. Optimized preparation conditions and surface analysis will be presented that demonstrates successful assembly of the coatings and characterizes their physicochemical properties. The antifouling properties were tested against a range of laboratory organisms such as diatoms and spores of algae and compared to protein resistance. The obtained trends will be discussed and correlated with field experiments in the real marine environment.
(1) Chen, S.; Jiang, S. 2008 A new avenue to nonfouling materials. Advanced Materials, 20, 335-338.
(2) Holmlin, R. E.; Chen, X. X.; Chapman, R. G.; Takayama, S.; Whitesides, G. M. 2001 Zwitterionic SAMs that resist nonspecific adsorption of protein from aqueous buffer. Langmuir, 17, 2841-2850.
(3) Chen, S. F.; Yu, F. C.; Yu, Q. M.; He, Y.; Jiang, S. Y. 2006 Strong resistance of a thin crystalline layer of balanced charged groups to protein adsorption. Langmuir, 22, 8186-8191.