AVS 58th Annual International Symposium and Exhibition
    Biomaterial Interfaces Division Monday Sessions
       Session BI-MoA

Paper BI-MoA9
La3+ doped TiO2 Nano-engineered Platforms for Biosensor

Monday, October 31, 2011, 4:40 pm, Room 108

Session: Sensors and Fluidics for Biomedical Applications
Presenter: Ravi Ranjan Pandey, Centre for Cellular and Molecular Biology, India
Authors: R.R. Pandey, Centre for Cellular and Molecular Biology, India
K.K. Saini, National Physical Laboratory, India
M. Dhayal, Centre for Cellular and Molecular Biology, India
Correspondent: Click to Email

The use of nanotechnology tools has opened new opportunities to explore analytical applications of the nano-engineered materials which attracted great attention due to their unique morphology, extraordinary physical and chemical properties towards development of biosensors to facilitate the improvement of the selectivity and sensitivity of the current methods. In this work, the importance of semiconducting La3+ doped TiO2 a metal-oxide-based nanostructure platform is highlighted for biosensors platforms. La3+ doped TiO2 nanostructure having nanometer-scale inner-core cavity which were exposed to the outer surface with different oxidation states having possibilities for redox-activity can make them attractive for sensing uses. Therefore, the use of La3+ doped TiO2 for the development of electrochemical sensors will be discussed. These platforms has been characterized by XRD, XPS, FTIR, SEM, cyclic voltametry to determine structure, surface chemistry and electron transfer characteristics for biosensor applications. Cholesterol oxidase immobilized onto La3+ doped TiO2-based nanostructured surfaces exhibited a pair of well-defined and quasireversible voltammetric peaks in CV measurements. We will also discuss the potential prospect of these surfaces as low cost stable platforms for biomedical diagnosis.