Many dispersions of colloidal particles with application in materials processing, biological assays, or medicine, contain elongated particles (e.g. ellipsoidal disks, rods, etc.) Recently these particles have been used in drug delivery applications because of the inability of leukocytes to easily rid them from the circulation. Moreover such particles are useful at the nanoscale for application in cancer therapies, either for detection of tumor vasculature or for the delivery of anti-cancer agents to tumor endothelial cells. Thus, the study of anisotropic particulate flows with adhesion in microchannels especially in mixtures with vesicle flows (i.e. red blood cells) has taken on a particularly important set of engineering applications. We will review our computer simulations of these processes with a view toward virtual prototyping and engineering these therapies.