AVS 56th International Symposium & Exhibition
    Biomaterial Interfaces Tuesday Sessions
       Session BI-TuP

Paper BI-TuP6
Fabrication and Characterization of Non-toxic and Non-Biofouling Plasma-Polymerized Polyethylene Glycol Thin Films

Tuesday, November 10, 2009, 6:00 pm, Room Hall 3

Session: Biomaterial Interfaces Poster Session I
Presenter: C. Choi, Sungkyunkwan University, Rep. of Korea
Authors: C. Choi, Sungkyunkwan University, Rep. of Korea
K.S. Kim, Sungkyunkwan University, Rep. of Korea
D. Jung, Sungkyunkwan University, Rep. of Korea
D.W. Moon, KRISS, Rep. of Korea
T.G. Lee, KRISS, Rep. of Korea
Correspondent: Click to Email

Polyethylene glycol (PEG) is a key molecule in the fabrication of non-biofouling surface for various biological applications such as biochips and tissue engineering. In particular, plasma-polymerized PEG (PP-PEG) thin films have many practical uses due to their strong adhesion onto any solid substrates. In this work, we fabricate PP-PEG thin films by using the capacitively coupled plasma chemical vapor deposition (CCP-CVD) method and non-toxic PEG200 molecules as a precursor. The surfaces of the PP-PEG thin films were characterized by using contact angle measurement, X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), Fourier transform infrared (FT-IR) spectroscopy and time-of-flight secondary ion mass spectrometry (TOF-SIMS). Our results show that PP-PEG thin film surfaces deposited at low plasma power were very similar in chemical composition to the PEG polymer surfaces. In addition, these PP-PEG surfaces showed excellent non-biofouling property and biocompatibility during in vitro and in vivo tests. These results indicate that our PP-PEG thin films would be useful for practical biological applications.