AVS 56th International Symposium & Exhibition
    Biomaterial Interfaces Wednesday Sessions
       Session BI+AS+BM+MS-WeM

Paper BI+AS+BM+MS-WeM5
Drop on Demand Ink Jet Methods for Development and Manufacturing of Array Based Sensors and Diagnostics

Wednesday, November 11, 2009, 9:20 am, Room K

Session: Array-Based Sensors and Diagnostics: Grand Challenges
Presenter: T.C. Tisone, BioDot Inc.
Authors: T.C. Tisone, BioDot Inc.
A.V. Lemmo, BioDot Inc.
Correspondent: Click to Email

The development and manufacturing of array based formats requires the transfer of biomarker reagents to a carrier substrate which forms the basis of a sensor for executing a multiplexed assay for research and diagnostics applications. The typical volume range for these types of assays is in the range of 100 pL up to 1000 nL: which lies in the range of commercial drop on demand piezoelectric and solenoid drop on demand dispensers. This presentation will discuss aspects of the physics and chemistry of successful applications of drop on demand methods to provide quantitative and high throughput reagent transfer to sensor substrates suitable for both Development and Manufacturing. Issues of drop formation, drop/substrate interactions and reagent/substrate interactions will be discussed. The agenda is to understand what role dispensing plays in the assay function.