AVS 55th International Symposium & Exhibition | |
BioMEMS Topical Conference | Tuesday Sessions |
Session BM-TuP |
Session: | BioMEMS |
Presenter: | K.J. Kwak, The Ohio State University |
Authors: | B. Bhushan, The Ohio State University K.J. Kwak, The Ohio State University S. Gupta, The Ohio State University S. Lee, The Ohio State University |
Correspondent: | Click to Email |
Protein layers are deployed over the surfaces of microdevices such as bioMEMS and bioimplants as functional layers that confer specific molecular recognition or binding properties or to facilitate biocompatibility with biological tissue. When a microdevice comes in contact with any exterior environment, like tissues and/or fluids with a variable pH, the biomolecules on its surface may get abraded. Silicon based bioMEMS are an important class of devices. Adhesion, friction and wear properties of biomolecules (e.g., proteins) on SAM coated silicon based surfaces are therefore important. These studies have been carried out on protein biomolecules using tapping mode AFM. Based on this study, adhesion, friction and wear mechanisms of biomolecules on SAM-coated silicon based surfaces are discussed.