| AVS 55th International Symposium & Exhibition | |
| Biomaterial Interfaces | Thursday Sessions |
| Session BI-ThP |
| Session: | Biomaterial Interfaces Poster Session with Focus on Engineered Bio-Interfaces and Sensors |
| Presenter: | C. Satriano, University of Catania, Italy |
| Authors: | C. Satriano, University of Catania, Italy G.M.L. Messina, University of Catania, Italy S. Svedhem, Chalmers University of Technology, Sweden G. Marletta, University of Catania, Italy B. Kasemo, Chalmers University of Technology, Sweden |
| Correspondent: | Click to Email |
A simple approach for preparation of smooth SiO2 surfaces by oxidative modification of polysiloxane films is described. Thin films of poly(hydroxymethylsiloxane) (PHMS) were deposited by spin coating on silicon or gold substrates and modified either by radiofrequency oxygen plasmas or combined oxygen plasmas and thermal treatments. The modified films were converted to SiOx phases, ultimately SiO2 like, as determined by XPS, and exhibited very high water wettability, as measured by contact angle measurements. Moreover, the high original flatness of the PHMS was not affected by the modification treatments. Both untreated and treated films had roughness values below one nanometer. Using the QCM-D and SPR techniques the adsorption behaviour of and supported lipid membrane (SLB) formation, from small unilamellar vesicles of neutral zwitterionic POPC, positively charged DOEPC and negatively charged DOPC/DOPS mixtures were investigated onto untreated and modified PHMS films. SLBs were successfully obtained on the modified PHMS surfaces. The latter results are compared with corresponding results for PVD deposited SiO2.