| AVS 55th International Symposium & Exhibition | |
| Biomaterial Interfaces | Thursday Sessions |
| Session BI-ThP |
| Session: | Biomaterial Interfaces Poster Session with Focus on Engineered Bio-Interfaces and Sensors |
| Presenter: | S.Y. Chen, Duke University |
| Authors: | S.Y. Chen, Duke University D.S. Sebba, Duke University A.A. Lazarides, Duke University |
| Correspondent: | Click to Email |
We present a theoretical and experimental study of surface-enhanced Raman scattering from core-satellite nanoparticle assemblies of known structure in the solution phase. The detectability of the Raman signal is attributed to enhanced electromagnetic fields localized between plasmonically coupled core and satellite metal nanoparticles. Design of the structures was accomplished using near field calculations based upon Generalized Mie theory, a theory that accurately accounts for multipolar coupling within clusters of spherical particles. Assembly structures are identified on the basis of positions of hot spots and overlap of plasmon resonance frequencies with Raman excitation spectra and available laser lines. Core-satellite structures are assembled using DNA linkers and characterized by transmission electron microscopy (TEM). The control of field strength and plasmon frequency provided by the coupled particle system is expected to provide insight into SERS signaling of use in application of SERS to biomolecule sensing.