AVS 54th International Symposium
    The Industrial Physics Forum 2007: The Energy Challenge Tuesday Sessions
       Session IPF-TuA

Invited Paper IPF-TuA4
Nanopores & Systems Biology

Tuesday, October 16, 2007, 2:40 pm, Room 602/603

Session: Frontiers in Physics
Presenter: J.J. Kasianowicz, National Institute of Standards and Technology
Authors: J.J. Kasianowicz, National Institute of Standards and Technology
J.W.F. Robertson, National Institute of Standards and Technology
O.V. Krasilnikov, UFPE, Recife, Brazil
V.M. Stanford, National Institute of Standards and Technology
Correspondent: Click to Email

Proteins that form nanometer-scale pores in cell membranes are the basis of many biological processes including nerve activity and cell-cell communication. Research over the past two decades demonstrated that they could also be used for the selective detection and characterization of molecules (e.g., proteins, anthrax toxins, and DNA). More recently, a single nanopore was used as the transducer for a novel aqueous-based mass spectrometry technique. The ability to detect and discriminate between molecules with nanopores should provide useful analytical systems for health care applications.