| AVS 54th International Symposium | |
| Biomaterial Interfaces | Tuesday Sessions |
| Session BI-TuP |
| Session: | Biomaterials Interfaces Poster Session |
| Presenter: | G. Saini, Brigham Young University |
| Authors: | M.R. Linford, Brigham Young University M.C. Asplund, Brigham Young University R. Gates, Brigham Young University F. Zhang, Brigham Young University G. Saini, Brigham Young University |
| Correspondent: | Click to Email |
Microlens arrays (MLAs) are powerful tools for surface modification. These commercially available optics offer a wide range of shapes and packings for their microlenses. Here we describe the use of MLAs for patterning monolayer-coated glass and silicon substrates. In this process, a nanosecond pulse of laser light is directed through a MLA. In the region where the microlenses focus the light onto the surface the protective monolayer is removed leaving a pattern of spots. A wide variety of proteins, including ferritin and ferritin analogs, adsorb directly onto these spots. A reactive polymer will also adsorb to these spots and undergo subsequent reactions that are typical of bioconjugate chemistry. This process is further demonstrated with 266 nm light on glass, where glass is the substrate material of choice for bioarrays.