| AVS 54th International Symposium | |
| Biomaterial Interfaces | Thursday Sessions |
| Session BI-ThP |
| Session: | Biomaterial Interfaces Poster Session |
| Presenter: | J. Hyun, Seoul National University, Korea |
| Authors: | J. Jung, Seoul National University, Korea J. Yuk, Kangwon National University, Korea K. Ha, Kangwon National University, Korea J. Hyun, Seoul National University, Korea |
| Correspondent: | Click to Email |
In this paper, we demonstrate a simple method to fabricate SPR imaging microarrays using polymer micropatterns. The use of thick polymeric micropatterns in imaging SPR microarray passivates the region by removing SPR signals completely or by saturating the SPR signal far beyond the detection range in SPR imaging. Two schemes to create polymeric micropatterns on the surface were demonstrated by micropatterning a thick insulating layer before depositing a metal layer or after depositing a metal layer. A biotin-streptavidin system was successfully performed to verify the systematic binding of biomolecules and the adsorption of cell culture media on the microarrays was quantitatively characterized. This SPR microarray can be applied in a variety of areas including protein adsorption, cell research, diagnosis of diseases, and more.