AVS 51st International Symposium
    Biomaterial Interfaces Monday Sessions
       Session BI-MoM

Paper BI-MoM4
Angle-resolved Imaging Surface Plasmon Resonance

Monday, November 15, 2004, 9:20 am, Room 210D

Session: In-Situ Spectroscopy of Biomolecules at Interface
Presenter: P.M. Williams, The University of Nottingham, UK
Authors: D.A. Armitage, The University of Nottingham, UK
P.M. Williams, The University of Nottingham, UK
Correspondent: Click to Email
Surface plasmon resonance (SPR) has evolved in recent years into a commercially recognized technique for analyzing surface interactions with a film thickness resolution on the sub-nanometer scale. SPR imaging can also be employed to obtain data on the spatial distribution of molecules at surfaces. However, the instrumentation currently used in SPR imaging experiments has reduced capabilities for precise SPR angle and hence thickness and refractive index measurements compared to conventional non-imaging systems. By combining a non-imaging SPR system with a micro-positioning stage we demonstrate that a 2-D image of SPR response can be produced whilst retaining high precision angle sensitivity.