Pacific Rim Symposium on Surfaces, Coatings and Interfaces (PacSurf 2014)
    Nanomaterials Wednesday Sessions
       Session NM-WeM

Paper NM-WeM6
Magnetoluminescent Nanoparticles For Detection And Treatment Of Cancer By Thermal Ablation

Wednesday, December 10, 2014, 9:40 am, Room Hau

Session: Nano Composites
Presenter: Nuyeli Izaguirre, Centro de Investigación Científica y de Educación Superior de Ensenada, Mexico
Authors: N. Izaguirre, Centro de Investigación Científica y de Educación Superior de Ensenada, Mexico
A. Hirata, Centro de Nanociencias y Nanotecnología, Universidad Nacional Autónoma de México, Mexico
Correspondent: Click to Email

In recent years has increased the interest for developing multifunctional materials which can be used for diagnosis and therapies for major diseases such as cancer. The purpose of this work is the synthesis and characterization of luminescent/magnetic nanoparticles (LMNPs) made of magnetite (Fe3O4) and their simultaneous combination with europium doped lanthanum oxide (La2O3:Eu), terbium doped lanthanum oxide (La2O3:Tb) or thulium doped lanthanum oxide (La2O3:Tm) for possible applications as contrast and thermal ablation agents in cancer treatment.

The method used to obtain the LMNPs is spray pyrolysis due it allows the synthesis of nanoparticles with narrow size distribution, adjustable size, high crystallinity and good stoichiometry. Luminescent nanoparticles were prepared with different concentration of dopant material and were post annealed at different temperatures in order to find the best luminescent response. Once obtained the luminescent materials with the highest luminescence, the synthesis of magnetoluminescent materials was followed. This second step was done for different concentration of luminescent and magnetic nanomaterials in order to obtain the best multifunctional properties material. The determination of the best material was made by characterizing the nanoparticles with different techniques such as spectrophotometry, X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and measurement of magnetic properties using a vibrating-sample magnetometer (VSM) and a magnetic induction device.

Partial support from CONACyT (Grant 100555) and DGAPA-UNAM (Grant IN-109913) and technical work provided by E. Aparicio, F. Ruíz and I. Gradilla is gratefully acknowledged.